Not likely. It's more likely she will contribute strongly in the background as a 'thought leader' and facilitator of political access for female candidates. Oprah is a speaker and activist -- somehow I get the feeling she wouldn't want to run a country.
Was just having this conversation with my partner. Part of what raises this issue is how low the bar 'running for president' has gotten to be. Heck, I've even thought I could do a better job than Orange Julius ... so someone who runs a media empire would certainly examine their skills and accomplishments against the current standard & conclude correctly that they could do a much better job. I think Oprah's decisions will ultimately hinge on where she feels she can plant her lever to accomplish the most. By 2020, the presidency may not be that place.
If Oprah were to consider a run for political office, it might make sense for her to make a run for Senate if there was an opening, and gain some legislative experience and then run in 2024. Though I don’t think there is a possibility in her home state and there is also the age issue, of course trumpy is 70ish so age may not be much of an issue these days.
Please, no more celebrities! There are countless people who have dedicated their lives in the selfless pursuit of community service. They are our future politicians, not famous, rich people. We must stop voting rich people into office. I can't emphasize enough how important it is for us to shift our focus from the glamorous, self serving, rich to people who have committed their lives to serving fellow Americans.
Further re: Oprah.
She is of considerable interest to others in the Democratic Party who think she would be a critically valuable candidate in a Southern State as a Senator, or Governor. This will be discussed, and debated. She might run in the very early informal stages of the Primaries, but the indicators are that she does not have office time in post, that would reassure voters. So, strong primary campaign interest, (she has not yet made up her mind) and some discussions for a possible State or Washington role. What might happen is an offer of a cabinet post, if the Democrats win, but this is not going to happen in 2020, sadly. The Morlocks will still have power.
I don't think Oprah will run for President. I do see her becoming more active politcally (sorry the only thing worst then my spelling is my typing) . She will speak at rallies and work to increase voter registration in the Southern states. People like her because she came from the deep south and has made something of her self. They listen to her because she has a strong message and terrific communication skills. In other words, she know how to get the message out and I think that wwill be her roll.