If any of my answers are redundant or come off as arrogant, I apologize. I am just trying to make sure I take the info in my head that has become second nature to me, and put it a way that everyone can understand without coming across as a know it all.
I really appreciate that, thanks! Sounds like the severity of side effects in response to the vaccine might be an indicator of how severe actual covid19 illness would have been for a person. Of course, unfortunately, I don't think there's a way to test this hypothesis though...
@mas1581 No apology needed. Expertise is not arrogance, and redundancy is often necessary to make sure people understand. :-) Thank you for all of the information.
It wouldn't show the most extreme cases, because it won't do enough damage to invoke a cytokine storm but the thought that it could show patients a basic idea of how sick they couldve gotten has crossed my mind many times. I just never stated it because I have 0 evidence whatsoever to back it up.
Thank you. Good to know and you're welcome. ?
Thank you Mas! Your detailed posts are very much appreciated, and you put it in layman's terms also ....
(And all this time we thought you were a plumber ...?)
If you knew what I did for a living, you'd be impressed with a plumber. Lol
My degree is in microbiology but I also played football in college. That led to a bad back injury(tore my lat clean off my spine) that forced me to rehab and pretty much teach myself how to walk again instead of going to grad school right after undergrad. Like the genius I am(not!), I decided to expand on my side hustle I'd been doing since I was 8-selling baseball cards and sports memorabilia. Between that and the contacts I picked up in college, I started a sports management company which both sells autographs/memorabilia and books athletes into autograph signing sessions. Ive been doing that for the past 20 years until the covid recession killed the business for me. I was going to go back and get a "real job" when I got married but when my wife got pregnant sooner than expected(our daughter is a honeymoon baby), we decided that sticking with this could allow me to be a stay at home parent too and the money difference was less than we'd spend for daycare. When she went into full day school, we started fostering and I've had infants and toddlers running around the house ever since.
Now that youre in the know, a plumber is much flashier than out of work baseball card dealer isn't it? Lol
O-mg, you need a vacation, Mas! Try to visualize a nice Carib getaway (w/ no hurricanes) on a beautiful pink sand beach, you and your sweetheart sipping a nice cooler and chillin'.... no small kids in sight ?
Peace my friend .....
Your answers are much appreciated!
Btw, based upon your previous remarks, do you think one's past severe reaction to the Shingrix vaccine shows a glimpse as to how likely one would have been to have gotten Shingles w/o the vaccine and how severe it would have been? What does the severity of a response to a vaccine imply? If an individual has a severe reaction to the Covid vaccine, for example, can that person assume they would have had a severe reaction to actually getting Covid? I've known numerous family members & friends who had a relatively minor reaction to Shingrix, whereas for me, I had a severe reaction. Kinda nervous now to take the Covid vaccine (although, of course, I will...) since I am triple risk. Am afraid I will become terribly sick. Any thoughts?
Your answers are much appreciated!
Btw, based upon your previous remarks, do you think one's past severe reaction to the Shingrix vaccine shows a glimpse as to how likely one would have been to have gotten Shingles w/o the vaccine and how severe it would have been?
I do not. The severity of shingle isn't related to your immune system as covid is showing to be. The worst covid infections are caused by the patient's immune system overreacting. Its not the case with shingles.
What does the severity of a response to a vaccine imply?
Usually nothing in relation to the severity of the disease itself. Covid, again, produces most of its damage by causing your immune system to attack your own body in a reaction that is way overboard, so it is different than pretty much anything else out there at this time
If an individual has a severe reaction to the Covid vaccine, for example, can that person assume they would have had a severe reaction to actually getting Covid?
Specific to covid, that assumption has the chance to be accurate. I cant come close to saying yes or no with any amount of certainty, but if that were the case it would not surprise me at all. It all depends on which genes in the rna strand are causing the immunological "malfunction" that leads to the most severe cytokine storm reactions.
I've known numerous family members & friends who had a relatively minor reaction to Shingrix, whereas for me, I had a severe reaction.
Genetics are usually the determining factor, but with the insane number of genes that go into an immune system along with the fact that they are changed with every offspring, heredity is something to take note of but won't be a true judge of it.
Kinda nervous now to take the Covid vaccine (although, of course, I will...) since I am triple risk. Am afraid I will become terribly sick. Any thoughts?
The worst reactions that have been seen thusfar are equivalent to a really bad 48 hour flu-fever, chills, muscle aches, headache, etc. Unless new reactions are seen when its distributed publically, thats as bad as you have to worry about. I assume if hospitalizations start to occur with the vaccine, the plug will be pulled pretty quickly and it will be months before the average person gets a chance to get one so we will see a lot more in terms of results before then. Just realize that you feeling sick isn't caused by covid, but your immune systems responding to it, so the threat of pneumonia, ventilators, strokes and other severe symptoms isn't there because its not a full virus.
As of now,, I would prepare to be laid up for 2 days as a worst case scenario but wouldn't worry about anything more unless your reaction to Shingrix was an allergic reaction. If it was an allergic reaction instead of an immune reaction, I would discuss it with your doctor in depth before taking it.
Many thanks for this information! Your insight and knowledge provided on this site is so helpful to many of us ... helps us to understand (in simpler terms) the gist of some pretty complex immunological mechanisms... much appreciated!